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What about other treatments that I hear about? The stage and grade of the cancer The chance that a type of treatment will cure the cancer or help in some way Your age Other health problems you have Your feelings about the treatment and the side effects that come with it Most of the time anal cancer is treated with both radiation pronounced RAY-dee-A-shun and chemotherapy KEY-mo-THAIR-uh-pee. Then the anus and part of the rectum are taken out, and sometimes nearby lymph nodes are taken out, too.